Isolation and Characterization of Antibacterial Compounds from Ganoderma boninense Against Methicillin-Resistant Staphylococcus aureus (MRSA)

Authors

  • Syahriel Abdullah
  • Ling Yee Soon
  • Sylvia Jerome Daim
  • Chong Khim Phin

DOI:

https://doi.org/10.51200/bjms.v12i.1361

Abstract

Background: Community and nosocomial-associated methicillin-resistant Staphylococcus aureus (MRSA) infections in Malaysian healthcare setting are terrifically increasing in recent years. There is an urgent need for an effective antibacterial agent to cope with this important issue. Due to the development of new antibiotics is not parallel with the increase of cases of infections, researchers have initiated isolation of compounds from natural resources to develop new potent therapeutic agent. Meanwhile, Ganoderma boninense is an oil palm devastating pathogen, which has been known to contain many bioactive compounds that might be potential to be developed as a new source of therapeutic agent.

Keywords: Ganoderma boninense, MRSA, Ergosterol, Ganoboninketal, antibacterial, dereplication

Author Biographies

Syahriel Abdullah

Biotechnology Programme, Faculty of Science and Natural Resources, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

Ling Yee Soon

Biotechnology Research Institute, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

Sylvia Jerome Daim

Pathobiology and Microbiology Department, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

Chong Khim Phin

Biotechnology Programme, Faculty of Science and Natural Resources, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

Downloads

Published

2018-09-21

How to Cite

Abdullah, S., Yee Soon, L., Daim, S. J., & Khim Phin, C. (2018). Isolation and Characterization of Antibacterial Compounds from Ganoderma boninense Against Methicillin-Resistant Staphylococcus aureus (MRSA). Borneo Journal of Medical Sciences (BJMS), 12, 11–12. https://doi.org/10.51200/bjms.v12i.1361
Total Views: 191 | Total Downloads: 121