Investigation of Phytochemicals and Antibacterial Activity of Persicaria odorata (L.) Methanolic Leaf Extract Against Selected Bacteria

Authors

  • Hartini Yusof
  • Emiriatulemni Suhemi
  • Aini Nabihah Mohd Rosdi
  • Nurhanis Syahira Shakir
  • Azrina Begam Mohd Ali
  • Zana Jamal Kareem

DOI:

https://doi.org/10.51200/bjms.v17i3.4255

Keywords:

antibacterial effect, phytochemical components, methanolic leaf extract, Persicaria odorata (L.)

Abstract

Multidrug-resistant microorganisms pose serious threats, especially to children from developing countries. Due to this concern, there is a greater need to develop potentially effective antibacterial agents from natural resources. This study aimed to investigate the phytochemical compounds of Persicaria odorata (L.) methanolic leaf extract and its antibacterial activity against selected bacteria. Agar well diffusion and broth microdilution were used to test gram-positive (Staphylococcus aureus and Bacillus cereus) and gram-negative bacteria (Salmonella enterica serovar typhimurium and Shigella flexneri). The bacteria were treated with P. odorata (L.) leaves extracted using methanol and diluted with 10% Dimethyl-sulfoxide (DMSO). P. odorata (L.) leaf extract was highly effective against S. aureus at a concentration of 1,000 mg/mL. Gram-positive bacteria had the lowest MIC and MBC values. The qualitative phytochemical analysis of the methanolic extract of P. odorata (L.) leaves indicated the presence of antibacterial compounds such as phenols, flavonoids, terpenoids, and tannins. In conclusion, P. odorata (L.) leaves which have been widely used in cuisines and traditional medicine also possess the potential to serve as an antibacterial agent.

Author Biographies

Hartini Yusof

Centre for Medical Laboratory Technology Studies,
Faculty of Health Sciences,
Universiti Teknologi MARA (UiTM),
Selangor Branch, Puncak Alam Campus,
Selangor Darul Ehsan, Malaysia


Emiriatulemni Suhemi

Centre for Medical Laboratory Technology Studies,
Faculty of Health Sciences,
Universiti Teknologi MARA (UiTM),
Selangor Branch, Puncak Alam Campus,
Selangor Darul Ehsan, Malaysia

Aini Nabihah Mohd Rosdi

Centre for Medical Laboratory Technology Studies,
Faculty of Health Sciences,
Universiti Teknologi MARA (UiTM),
Selangor Branch, Puncak Alam Campus,
Selangor Darul Ehsan, Malaysia



Nurhanis Syahira Shakir

Centre for Medical Laboratory Technology Studies,
Faculty of Health Sciences,
Universiti Teknologi MARA (UiTM),
Selangor Branch, Puncak Alam Campus,
Selangor Darul Ehsan, Malaysia



Azrina Begam Mohd Ali

Apical Scientific Sdn Bhd,
Seri Kembangan, Selangor, Malaysia

 

Zana Jamal Kareem

Faculty of Health Science,
Qaiwan International University (QIU),
Slemani Heights, Sulaymaniyah, Iraq

 

Kurdistan Institution for Strategic Studies
and Scientific Research (KISSR),
335 Shorsh St, Iraq

hartinieyusof@gmail.com

Published

2023-09-30

How to Cite

Hartini Yusof, Emiriatulemni Suhemi, Aini Nabihah Mohd Rosdi, Nurhanis Syahira Shakir, Azrina Begam Mohd Ali, & Zana Jamal Kareem. (2023). Investigation of Phytochemicals and Antibacterial Activity of Persicaria odorata (L.) Methanolic Leaf Extract Against Selected Bacteria. Borneo Journal of Medical Sciences (BJMS), 17(3), 12–22. https://doi.org/10.51200/bjms.v17i3.4255
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